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The quality of any tracking-by-assignment hinges on the accuracy of the foregoing target detection / segmentation step. In many kinds of images, errors in this first stage are unavoidable. These errors then propagate to, and corrupt, the tracking result. Our main contribution is the first probabilistic graphical model that can explicitly account for over-(More)
Tracking by assignment is well suited for tracking a varying number of divisible cells, but suffers from false positive detections. We reformulate tracking by assignment as a chain graph–a mixed directed-undirected probabilistic graphical model–and obtain a tracking simultaneously over all time steps from the maximum a-posteriori configuration. The model is(More)
MOTIVATION To gain fundamental insight into the development of embryos, biologists seek to understand the fate of each and every embryonic cell. For the generation of cell tracks in embryogenesis, so-called tracking-by-assignment methods are flexible approaches. However, as every two-stage approach, they suffer from irrevocable errors propagated from the(More)
We use weakly supervised structured learning to track and disambiguate the identity of multiple indistinguishable, translucent and deformable objects that can overlap for many frames. For this challenging problem, we propose a novel model which handles occlusions, complex motions and non-rigid deformations by jointly optimizing the flows of multiple latent(More)
One distinguishing property of life is its temporal dynamics, and it is hence only natural that time lapse experiments play a crucial role in modern biomedical research areas such as signaling pathways, drug discovery or developmental biology. Such experiments yield a very large number of images that encode complex cellular activities, and reliable(More)
We propose a novel mixtures of Gaussian processes model in which the gating function is interconnected with a probabilistic logical model, in our case Markov logic networks. In this way, the resulting mixed graphical model, called Markov logic mixtures of Gaussian processes (MLxGP), solves joint Bayesian non-parametric regression and probabilistic(More)
Automated cell tracking methods are still error-prone. On very large data sets, uncertainty measures are thus needed to guide the expert to the most ambiguous events so these can be corrected with minimal effort. We present two easy-to-use methods to sample multiple proposal solutions from a tracking-by-assignment graphical model and experimentally evaluate(More)
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