Martin Pieprzyk

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Cell surface proteins are excellent targets for diagnostic and therapeutic interventions. By using bioinformatics tools, we generated a catalog of 3,702 transmembrane proteins located at the surface of human cells (human cell surfaceome). We explored the genetic diversity of the human cell surfaceome at different levels, including the distribution of(More)
loaded, in triplicate, into 45 sample inlets, and 48 primer/probes (each a combination of forward and reverse PCR primers specific One of the hottest trends today in life sciences is the analyses of individual cells. What researchers are finding is that each cell needs to be treated as an individual because cells are not necessarily in the same state at(More)
INTRODUCTION Cell surface proteins are ideal targets for cancer therapy and diagnosis. We have identified a set of more than 3700 genes that code for transmembrane proteins believed to be at human cell surface. METHODS We used a high-throuput qPCR system for the analysis of 573 cell surface protein-coding genes in 12 primary breast tumors, 8 breast cell(More)
Heart and vascular endothelial cells from human pluripotent stem cells are of interest for applications in cell therapy and cardiovascular disease. Differentiation protocols are now sufficiently refined that production of cardiomyocytes, endothelial-and smooth muscle cells is fairly efficient and reproducible. Genetically marked hESCs have been produced in(More)
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