Learn More
Motivation Two types of reasoning • Reasoning is one key feature when using ontologies • Reasoning means to create new knowledge by inferring facts that are implicitly given by the existing data • scaleable and fast reasoning can still be a challenging task, depending on • the dataset (structure, number of triples) • the used ontology language • different(More)
Vascular endothelial growth factor (VEGF) has been shown to be a potent mediator of angiogenesis that functions as a survival factor for endothelial cells by up-regulating Bcl-2 expression. We have recently reported that human dermal microvascular endothelial cells (HDMECs) seeded in biodegradable sponges and implanted into severe combined immunodeficient(More)
In order to enable the semantic web as well as other time critical semantic applications, scaleable reasoning mechanisms are indispensable. To address this issue, in this paper we propose a rule-based reasoning algorithm which explores the highly parallel hardware of modern processors. In contrast to other approaches of parallel reasoning, our algorithm(More)
Schmallenberg virus (SBV) is a recently discovered Bunyavirus associated mainly with abortions, stillbirths and malformations of the skeletal and central nervous system (CNS) in newborn ruminants. In this study, a detailed immunophenotyping of the inflammatory cells of the CNS of affected animals was carried out in order to increase our understanding of SBV(More)
BACKGROUND Coxiella burnetii is the causative agent of Q-fever, a widespread zoonosis. Due to its high environmental stability and infectivity it is regarded as a category B biological weapon agent. In domestic animals infection remains either asymptomatic or presents as infertility or abortion. Clinical presentation in humans can range from mild flu-like(More)
Corynebacterium ulcerans may cause diphtheria in humans and caseous lymphadenitis in animals. We isolated nontoxigenic tox-bearing C. ulcerans from 13 game animals in Germany. Our results indicate a role for game animals as reservoirs for zoonotic C. ulcerans.
Tularemia is a zoonotic disease caused by Francisella tularensis that has been found in many different vertebrates. In Germany most human infections are caused by contact with infected European brown hares (Lepus europaeus). The aim of this study was to elucidate the epidemiology of tularemia in hares using phenotypic and genotypic characteristics of F.(More)
Sharing in silico experiments is essential for the advance of research in computational biology. Consequently, the COMBINE archive was designed as a digital container format. It eases the management of files related to a modelling result, fosters collaboration, and ultimately enables the exchange of reproducible simulation studies. However, manual handling(More)
For the development of variable systems, software product lines (SPL) are an established way to handle the variability by using feature models. Nevertheless, the configuration of an SPL can be complex, especially if a product line consists of a large number of features. The problem of handling the complexity becomes even more sophisticated if not only(More)