Martin Larsson

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The method of posthaemorrhagic blood volume (BV) determination by simple haematocrit measurement has been compared with the conventional isotope dilution technique. 51Cr tagged erythrocytes and 125IHSA were used to estimate RBC volume and plasma volume in non-starved male Sprague-Dawley rats. Two series of experiments were carried out by two different(More)
A hydrogel compound (Sauflex, Special Polymers Ltd., London) which has the capacity to swell by absorbing surrounding fluid, was found to be capable of absorbing prostaglandins (PGE1, PGF2 alpha) in alcohol or saline during this process. After evaporation of the hydratized hydrogelic compound which restored its initial proportions and stiffness,(More)
A single bout of low-frequency electroacupuncture (EA) causing muscle contractions increases whole-body glucose uptake in insulin-resistant rats. We explored the underlying mechanism of this finding and whether it can be translated into clinical settings. Changes in glucose infusion rate (GIR) were measured by euglycemic-hyperinsulinemic clamp during and(More)
An isotonic fluid load was given to rats by infusing 12 ml saline i.v. in 60 min. The plasma water and extracellular fluid volumes of the whole animal and selected tissues were subsequently studied with 125I human serum albumin and 51Cr EDTA. The fluid infused was equivalent to 130% of the plasma water volume. The total extracellular fluid volume increased(More)
The antipsychotic effect ofα-methyltyrosine (α-MT) in combination with thioridazine was investigated by means of rating scales for “social behaviour” and “mental symptoms” The clinical effect was also evaluated in relation to the serum concentrations ofα-MT and thioridazine and to the increase in prolactin secretion in response to the interaction with(More)
Liver glycogen content, blood glucose, insulin, glucagon, and epinephrine were determined during 1 h hemorrhagic hypotension at 60 mmHg and 23 h thereafter in fed and two groups of 24-h food-deprived rats receiving either no infusion or 30% glucose intravenously during hemorrhage. Liver glycogen content was reduced by greater than 90% after 24-h food(More)
A method has been developed for the quantitative determination of haloperidol in brain and other tissues. Such determinations have been made after acute and chronic administration of haloperidol to Sprague-Dawley rats. Different regions of the brain including the striatum, the limbic forebrain and the cerebellum have been analyzed separately. The(More)
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