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  • Martin L. Biniossek, Dorit K. Nägler, Christoph Becker-Pauly, Oliver Schilling
  • Biology, Medicine
  • Journal of proteome research
  • 2011 (First Publication: 2 December 2011)
  • Cysteine cathepsins mediate proteome homeostasis and have pivotal functions in diseases such as cancer. To better understand substrate recognition by cathepsins B, L, and S, we applied proteomicContinue Reading
  • Maria Magdalena Koczorowska, Stefan Tholen, +8 authors Oliver Schilling
  • Biology, Medicine
  • Molecular oncology
  • 2016
  • Cancer associated fibroblasts (CAFs) constitute an abundant stromal component of most solid tumors. Fibroblast activation protein (FAP) α is a cell surface protease that is expressed by CAFs. WeContinue Reading
  • Hasmik Shahinian, D Loessner, +4 authors Oliver Schilling
  • Biology, Medicine
  • Molecular oncology
  • 2014 (First Publication: 1 October 2013)
  • Kallikrein‐related peptidases, in particular KLK4, 5, 6 and 7 (4–7), often have elevated expression levels in ovarian cancer. In OV‐MZ‐6 ovarian cancer cells, combined expression of KLK4–7 reducesContinue Reading
  • Susanne Elfert, Andreas Weise, +4 authors Andreas Hecht
  • Biology, Medicine
  • PloS one
  • 2013 (First Publication: 15 April 2013)
  • The members of the TCF/LEF family of DNA-binding proteins are components of diverse gene regulatory networks. As nuclear effectors of Wnt/β-catenin signaling they act as assembly platforms forContinue Reading
  • Costel C Darie, Martin L. Biniossek, Veronika Winter, Bettina Mutschler, Wolfgang Haehnel
  • Biology, Medicine
  • The FEBS journal
  • 2005 (First Publication: 13 May 2005)
  • Complex I (NADH: ubiquinone oxidoreductase) is the first complex in the respiratory electron transport chain. Homologs of this complex exist in bacteria, mitochondria and chloroplasts. The minimalContinue Reading