Martin Löffler

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Fusarium head blight (FHB) in wheat results in reduced yield and quality and in accumulation of mycotoxins. The objective of this study was to identify genomic regions in wheat involved in the control of FHB resistance applying a QTL meta-analysis approach by combining QTL of 30 mapping populations to propose independent meta-QTL (MQTL). A consensus map was(More)
alpha-Methylacyl-CoA racemase (AMACR) has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer (PCa). However, AMACR expression was down-regulated at the transcript and protein level in hormone-refractory metastatic PCa, suggesting a hormone-dependent expression of AMACR. To further explore the(More)
Fusarium graminearum (FG) and F. verticillioides (FV) produce the mycotoxins deoxynivalenol (DON), zearalenone (ZEA) and fumonisins (FUM), respectively, in maize. The EU released limits for these toxins in food. Growing resistant varieties is one alternative to fulfill these limits. Quantification of mycotoxin concentrations is expensive and time consuming.(More)
Infection of maize ears with Fusarium graminearum (FG) and Fusarium verticillioides (FV) reduces yield and quality by mycotoxin contamination. Breeding and growing varieties resistant to both Fusarium spp. is the best alternative to minimize problems. The objectives of our study were to draw conclusions on breeding for ear rot resistance by estimating(More)
OBJECTIVES This study set out to examine the efficacy and tolerability of two innovative implant forms of leuprorelin acetate in men with advanced hormone-dependent prostate cancer in everyday clinical practice. METHODS Data were collected from 818 patients (from 273 centers across Germany) who were pretreated with slow-release luteinizing(More)
Fusarium spp. in maize can contaminate grain with mycotoxins harmful to humans and animals. Breeding and growing resistant varieties is one alternative to reduce contamination by mycotoxins. Little is known about the population parameters relevant to resistance breeding. The objectives of this study were to draw conclusions on breeding of reduced mycotoxin(More)
Building on our previous work [Taubert et al. 2012], we present an approach for real-time interaction between a real human and an avatar. We generate reactive motions by a dynamical extension of a hierarchical Gaussian process latent variable model, including latent dimensions for emotional style variation and target positions. This allows the avatar to(More)
PURPOSE Lower ureteral calculi are accessible by transrectal endo-ultrasound, including 3-dimensional image processing with surface rendering. We analyzed the efficiency of this innovative technology compared with that of standard radiographic examinations with respect to the outcome of extracorporeal shock wave lithotripsy (ESWL) (Dornier Medical Systems,(More)
The importance of a safer approach to the abdominal cavity has led to several developments in the field of trocars, cannulae and puncture techniques. Examples are the insertion of a needle scope into a Veress needle, complex access cannulae and our new principle of using an "optical scalpel". In our view, direct optical visualization and actively(More)
This paper presents an integrated method for the simulation of mixed 1D / 3D system models in the domain of building energy supply systems. The feasibility of this approach is demonstrated by the use case of a solar thermal system: the sub-model of a hot water storage is modeled as a detailed threedimensional CFD model, but the rest of the system model(More)