This paper describes a new method for the ontologically based standardization of concepts with regard to the quality assurance of clinical trial protocols. We developed a data dictionary for medical and trial-specific terms in which concepts and relations are defined context-dependently. The data dictionary is provided to different medical research networks… (More)
The domain of hemato-oncology is characterized by a complex and data-intensive treatment and the involvement of geographically distributed institutions (e.g. oncological ward, central commission, external panels) in the context of protocol-directed trials. Current research efforts in this domain (e.g. [1-3]) focus on specialized subtasks such as… (More)
Building on our previous work [Taubert et al. 2012], we present an approach for real-time interaction between a real human and an avatar. We generate reactive motions by a dynamical extension of a hierarchical Gaussian process latent variable model, including latent dimensions for emotional style variation and target positions. This allows the avatar to… (More)
This paper presents an integrated method for the simulation of mixed 1D / 3D system models in the domain of building energy supply systems. The feasibility of this approach is demonstrated by the use case of a solar thermal system: the sub-model of a hot water storage is modeled as a detailed three-dimensional CFD model, but the rest of the system model… (More)
Abschlussbericht zu einem vom BMBF geförderten Verbundvorhaben mit den Förderkennzeichen 01IS08013A, 01IS08013B und 01IS08013C Das diesem Bericht zugrunde liegende Vorhaben wurde mit Mitteln des Bundesministeriums für Bildung und Forschung gefördert. Die Verantwortung für den Inhalt dieser Veröffent-lichung liegt bei den Autoren.
The domain of hemato-oncology is characterized by a complex patient management and the involvement of several institutions (e.g. oncological ward, private practitioner, external review panels) in the context of protocol-directed trials. Current research efforts in this domain (e.g. [1-3]) focus on specialized subtasks such as chemotherapy dose calculation… (More)