OBJECTIVE To evaluate marker distribution of free beta-human chorionic gonadotrophin (fbeta-hCG) and pregnancy-associated plasma protein-A (PAPP-A) in singleton pregnancies conceived by assisted reproduction techniques (ART). METHODS In vitro fertilization (IVF) (n = 203) and intracytoplasmic sperm injection (ICSI) (n = 192) cases from a database of 14… (More)
This paper describes developments and experience in the ESPRIT project 1283: " VDM for Interfaces of the PCTE ". It shows the way temporal logic is used in combination with the relational VDM method in order to write interface specifications for large reactive systems. It is shown tlhat in this way a specification can be written both usable for… (More)
In order to get more insight into the mechanism by which the onset of puberty is controlled, a developmental study on the displacement of catalase- and dopamine-containing cells in the hypothalamic region was done in rats which received a neonatal lesion of the suprachiasmatic nucleus. The displacement of cells is delayed after these lesions. However, the… (More)
A method is described in which food approach behaviour of rats is recorded to study feeding behaviour. Between rats, differences in food approach behaviour were observed. For each rat, food approach behaviour was constant over a long period of time. This allows conversion of approach behaviour data into quantified feeding behaviour. Examples of long-term… (More)
Up to 84 days there was no difference in growth between groups of rats kept from birth at 8:16, 12:12 or 18:6 hours light:dark. More eating activity takes place during the light period when this is a larger part of the 24 hour day.