Martin Kříž

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The effects of prostaglandins E1, E2, F1alpha, and F2alpha on prolactin and growth hormone synthesis and secretion were studied in cultured rat pituitary cells. Total extracellular accumulation of prolactin was measured by radioimmunoassay. When hormone synthesis was studied, the cells were cultured in the presence of [3H]leucine for the last hour of each(More)
We have studied the relationship between the prolaction (PRL) release induced by thyroliberin (TRH) and theophylline and the formation and inactivation of adenosine 3', 5'-cyclic monophosphate (cyclic AMP) in cultured rat-pituitary cells (GH3 cells). TRH, which stimulated prolactin release, increased cyclic AMP formation and stimulated transiently both the(More)
Human fibroblast activation protein (FAP), a member of the serine prolyl oligopeptidase family, is a type II cell surface glycoprotein selectively expressed by fibroblastic cells in areas of active tissue remodeling, such as the embryonic mesenchyme, areas of wound healing, the gravid uterus, and the reactive stroma of epithelial cancers. Homologues of FAP(More)
Human Fibroblast Activation Protein (FAP), a member of the serine prolyl oligopeptidase family, is a type II cell surface glycoprotein that acts as a dual-specificity dipeptidyl-peptidase (DPP) and collagenase in vitro. Its restricted expression pattern in embryonic mesenchyme, in wound healing and in reactive stromal fibroblasts of epithelial cancers, has(More)
Previous studies have demonstrated a marked change in the metabolism of phospholipids (PL) after activation of resting B lymphocytes with anti-immunoglobulin (anti-Ig). In this study we examined PL metabolism in highly purified trinitrophenyl (TNP)-binding B cells after their activation with various forms of TNP-carrier protein. Such cells show similar(More)
Stochastic methods for ADC (analogue-to-digital converter) tests have been developed to enable testing of precise AD converters that are difficult to test by standard methods using deterministic signal. A transportable high stable reference AD device was designed and realised for a comparison of systems for testing a dynamic quality of ADCs or AD modules(More)