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OBJECTIVE To determine the contribution of inheritance to the incidence of squamous cell carcinoma of the head and neck. DESIGN Historical cohort study. First degree relatives of cases with squamous cell carcinoma of the head and neck made up the exposed cohort and first degree relatives of spouses of cases made up the comparison unexposed cohort. (More)
A retrospective study of 126 patients who underwent total laryngectomy during a 10-year period was carried out. The incidence of post-laryngectomy pharyngo-cutaneous fistula was 19%. Pre-operative radiotherapy appears to be a risk factor when surgery is performed within three months of completion of radiotherapy. Intra-operative blood transfusion is(More)
BACKGROUND Monitoring for hypocalcemia after thyroidectomy, using only symptoms and serum calcium levels, can delay the discharge of patients who will remain normocalcemic and can delay the treatment of hypocalcemic patients. STUDY DESIGN We conducted a systematic search for articles describing use of parathyroid hormone (PTH) assay, checked within hours(More)
The objective of the present study was to examine the association between human papillomavirus (HPV) infection and risk of developing oral cancer. The investigation followed a hospital-based case-control design. Cases consisted of newly diagnosed patients with squamous cell carcinoma of the oral cavity and oropharynx. Controls were frequency matched to(More)
Despite the belief that cancer mortality can be reduced if lesions are detected, diagnosed and treated at an early stage, only one study, among a number concerning cancers of the upper aerodigestive tract (UADT), has found any relationship between such delays and prognosis for this population of cancer patients. The aim of this study was, therefore, to(More)
To test the feasibility of providing a psycho-educational intervention for people with head and neck (H&N) cancer. A prospective non-randomized design was used. Subjects were patients with H&N cancer. They were offered the Nucare coping strategies program in one of three formats: small group and one-to-one formats with therapists; and a home format, with(More)
OBJECTIVES To evaluate levels of parathyroid hormone following total thyroidectomy in order to ascertain its ability to predict postoperative hypocalcemia. To establish standardized criteria permitting the safe discharge of total thyroidectomy patients within 13 hours of surgery. METHODS This is a prospective study in which parathyroid hormone levels were(More)
OBJECTIVE Previous studies have established the efficacy of post-thyroidectomy hypocalcemia monitoring using parathyroid hormone (PTH) and corrected calcium levels at 1 and 6 hours. The goal of this study was to measure the impact of managing patients based on the above findings with respect to: duration of hospital stays, rates of transient hypocalcemia,(More)
BACKGROUND Parathyroid hormone (PTH) levels up to 6 hours postthyroidectomy have been shown to have excellent predictive power in determining hypocalcemia. In this study, we investigate the usefulness of combining calcium and PTH to increase the predictive power. METHODS Individual patient data were obtained from 3 studies (152 patients) that fulfilled(More)