Martin J.B. Taphoorn

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PURPOSE In this single center study, we aimed to assess quality of life and cognitive and emotional distress in patients treated for high-grade glioma. METHODS AND MATERIALS A hundred and eighteen patients with high-grade glioma were prospectively enrolled. We assessed HRQoL at baseline (after surgery before radiotherapy), at the end of radiotherapy and(More)
BACKGROUND Our previous study on cognitive functioning among 195 patients with low-grade glioma (LGG) a mean of 6 years after diagnosis suggested that the tumour itself, rather than the radiotherapy used to treat it, has the most deleterious effect on cognitive functioning; only high fraction dose radiotherapy (>2 Gy) resulted in significant added cognitive(More)
" [If effective treatment] would result in deterioration of cerebral functioning and, subsequently, in worse health-related quality of life, longer survival is less meaningful. " Improved, personalized treatment of glioma necessitates long-term follow-up of cognitive functioning Over the last few decades, substantial progress has been made in the treatment(More)
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