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An impediment to Web-based retail sales is the impersonal nature of Web-based shopping. A solution to this problem is to use an avatar to deliver product information. An avatar is a graphic representation that can be animated by means of computer technology. Study 1 shows that using an avatar sales agent leads to more satisfaction with the retailer, a more(More)
There is increasing evidence for the role of the autonomic nervous system in the control of adrenal cortical function although the nature of the innervation is as yet unknown. In view of our expanding knowledge of the roles which peptidergic putative transmitters play in the autonomic nervous system, the present study was adrenal gland. Using(More)
Using in vitro autoradiography, 125I-VIP binding was found to be concentrated in the capsule and glomerulosa of the rat adrenal cortex. The densest receptor distribution was coincident with the distribution of VIP nerve fibers that arborize extensively in the capsule and glomerulosa. The specificity of this binding was demonstrated using unlabelled VIP,(More)
There is now convincing evidence for the distribution of several nerve plexuses in the outer zone of the adrenal cortex. At the ultrastructural level, the close proximity of nerve boutons to cortical cells establishes the anatomical substrate for a direct neural effect on adrenal cortical cell functions. Of those neurotransmitters and neuropeptides(More)
Previous results from this laboratory have suggested that neurons in the ventrolateral medulla (VLM) modulate the pressor response to muscular contraction. The purpose of the present study was to determine 1) if VLM neurons with a discharge pattern related to sympathetic discharge and/or the cardiac cycle are stimulated during muscular contraction, 2) if(More)
Regeneration of rat adrenals was studied after bilateral enucleation to determine whether there is a neural component mediating this process as there is in compensatory adrenal growth after unilateral adrenalectomy. Regeneration was approximately 50% complete (based on criteria of wet weight and DNA content) by 10 days after enucleation; at this time(More)
Immunoreactive serotonin is demonstrated to be present in 75% of rat adrenal medullary cells using an antibody to serotonin and peroxidase-antiperoxidase immunocytochemical method. The concentration of serotonin in rat adrenals was found to be 7.7 +/- 0.1 X 10(-6) mol/kg wet weight by high-performance liquid chromatography with electrochemical detection.(More)
Genetic factors play an important role in the pathogenesis of type 2 diabetes. The relevance to type 2 diabetes of the common polymorphism Glu23Lys in the potassium inward rectifier 6.2 (KIR6.2) gene is still controversial. The aim of this study was to assess whether this polymorphism influences beta-cell function, alpha-cell function, or insulin action. We(More)
BACKGROUND A reduction in gamma-aminobutyric (GABA)-mediated inhibition of pressor sites in the caudal hypothalamus of spontaneously hypertensive rats compared with that of normotensive Wistar-Kyoto rats has recently been demonstrated. OBJECTIVE To determine whether the reduction in GABA-mediated inhibition of the caudal hypothalamus of the spontaneously(More)
Previous immunocytochemical studies at the light microscopic level have demonstrated serotonin immunoreactivity in rat adrenal epinephrine-containing cells. In this study we have used electron microscopic immunocytochemical methods to study the subcellular distribution of serotonin and the enzyme responsible for epinephrine biosynthesis,(More)