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Agitation, aggression, and psychosis are among the most troublesome behavioral and psychological symptoms of dementia (BPSD) and impair the lives of dementia patients and their caregivers. Atypical antipsychotics have been widely prescribed to improve these BPSD. However, in a number of trials with atypical antipsychotics, a consistent increase in overall(More)
OBJECTIVE To evaluate a novel specific psychological intervention aimed at improving coping in patients with systemic lupus erythematosus (SLE). METHODS 34 community living SLE patients were recruited for the study. Intervention was undertaken in groups of up to eight patients and in two blocks over six months each. Eight patients were enrolled as a(More)
From the perspective offered by diagnostic criteria, cognitive rating scales and psychometric tests, Alzheimer's disease appears to be primarily a continuous decline of memory and intelligence. Changes in other areas of behaviour often go unrecognized at examination or are considered insignificant. A completely different view is offered by the reports of(More)
Anhand einer Falldiskussion eines 82jährigen Mannes mit einem fortgeschrittenen dementiellen Syndrom wird das Problem der Sterbehilfe im klinischen Alltag erörtert. Einzelfallbezogene ethische Entscheidungsprozesse auf dem Hintergrund bestehender gesetzlicher Regelungen und standesrechtlicher Gebote werden dargestellt. Die Bedeutung der individuellen(More)
Die Patientenverfügung und die Bevollmächtigung in gesundheitlichen Angelegenheiten sind zwei in ihrer rechtlichen Verbindlichkeit gegenwärtig noch ungeklärte Instrumente, mit denen eine Person über den Zeitpunkt eines krankheitsbedingten Verlustes ihrer Einwilligungsfähigkeit hinaus Einfluß auf sie betreffende medizinische Entscheidungen nehmen kann. Im(More)
Many studies have demonstrated an association between the apolipoprotein E (apoE) epsilon 4 allele and Alzheimer's disease (AD). The present study is concerned with the relationship between the apoE epsilon 4 allele and the progression of symptoms in AD. We determined rates of cognitive decline and deterioration in everyday performance prospectively over 3(More)
Alcohol abuse and alcohol dependence are frequent disorders in the elderly. The disorders often develop as a response to burdensome life events which have to be treated specifically. Old alcoholics often respond well to age-specific interventions, if co-existing depressive symptoms are also treated. Because of the non-specific nature of the initial(More)
OBJECTIVES It has been convincingly demonstrated that in dementia, psychoeducative group intervention with caregivers positively impacts on motivation for care and satisfaction of the caregivers. It has, however, been neglected to examine the effect of psychoeducative group intervention on the behavioural and psychological symptoms of the demented patients.(More)