The bactericidal/permeability-increasing protein (BPI) of polymorphonuclear leukocytes (PMN) is a potent cytotoxin, specific for Gram-negative bacteria, that also inhibits endotoxin activity by neutralizing isolated bacterial lipopolysaccharides (LPS). We have previously shown that an isolated 25 kD N-terminal fragment of human BPI carries all the… (More)
without extensive prior release of endotoxin.
This paper presents a comprehensive exploration of an Internal Medicine outpatient clinic practice setting by applying discrete event simulation (DES) modeling. Growing demands on outpatient clinics require greater emphasis on enhancing performance and optimizing resource utilization. Therefore, a data collection plan was designed to capture total patient… (More)