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Although combination therapy for HIV infection represents a triumph for modern medicine, chronic suppressive therapy is required to contain persistent infection in reservoirs such as latently infected CD4+ lymphocytes and cells of the macrophage-monocyte lineage. Despite its success, chronic suppressive therapy is limited by its cost, the requirement of(More)
BACKGROUND Poor performance on mobility testing is one of a number of factors associated with increased falls in community-dwelling elderly. The significance of these associations has not previously been tested in a sample drawn exclusively from a primary care practice. METHODS This 1-year prospective study recorded falls, fall injuries, and related(More)
A prospective study was developed to examine whether personality factors predispose runners to injury. Forty runners who completed a type A behavior screening were followed for 1 year during which they documented their training mileage, injuries, and time lost from training because of injury. Runners with high scores on the type A behavior screening(More)
BACKGROUND This 1-year prospective study examined the accuracy of patient recall of falls and fall injuries and completeness of chart documentation of these events. METHODS One hundred ambulatory geriatric family practice patients reported falls weekly by postcard with telephone call follow-up. On a final postcard they reported their recall of falls and(More)
The development of multi-drug combination therapy for treatment of HIV disease is considered one of the great success stories of modern medicine. In a period of approximately ten years, the death rate from HIV disease was reduced by 50 to 80% and changed from a nearly universally fatal and catastrophic illness to what is now often a manageable chronic(More)