Martha C Ma

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In vitro dissolution equivalence has been assessed through profile comparison between the test and reference formulations for postapproval changes. Functions of the absolute mean difference and average squared mean differences were two of the often-used criteria to evaluate distance or similarity between general profiles. The two functions and their method(More)
1 Supported by The Boeing Company under Illinois Technology Challenge Grant 03-115. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the views of The Boeing Company or the State of Illinois. Portions of this document have been independently published and are c 2003(More)
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