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How neurons make specific synaptic connections is a central question in neurobiology. The targeting of the Drosophila R7 and R8 photoreceptor axons to different synaptic layers in the brain provides a model with which to explore the genetic programs regulating target specificity. In principle this can be accomplished by cell-type-specific molecules(More)
The formation of neuronal connections requires the precise guidance of developing axons toward their targets. In the Drosophila visual system, photoreceptor neurons (R cells) project from the eye into the brain. These cells are grouped into some 750 clusters comprised of eight photoreceptors or R cells each. R cells fall into three classes: R1 to R6, R7,(More)
Information processing relies on precise patterns of synapses between neurons. The cellular recognition mechanisms regulating this specificity are poorly understood. In the medulla of the Drosophila visual system, different neurons form synaptic connections in different layers. Here, we sought to identify candidate cell recognition molecules underlying this(More)
Els resultats d'aquesta Tesi doctoral s'han dividit en tres capítols. El primer capítol engloba dos articles publicats; el segon, un article enviat; i el tercer, un article publicat. A cada capítol s'ha inclòs un apartat de precedents i un resum de cada article. Quan s'ha considerat necessari s'ha inclòs una breu introducció a la temàtica que es tractarà(More)
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