Learn More
The two techniques of flow cytometry analysis (FCM) and immunohistochemical localisation of bromodeoxyuridine (BrdUrd) incorporation after in vivo administration, were combined to study proliferation in squamous cell carcinoma of the head and neck region. Care was taken in this study to ensure that similar material was processed using both techniques such(More)
OBJECTIVE To analyse the risk of second primary cancers during long term follow up of patients with Hodgkin's disease. DESIGN Cohort study. SETTING The British National Lymphoma Investigation (a collaborative group of over 60 participating centres in Britain treating lymphomas). PATIENTS 2846 patients first treated for Hodgkin's disease during(More)
OBJECTIVE To determine the effects on cessation rates of adding a partner support group component to a large-group community-based behavioral smoking cessation program. METHODS During the past eight smoking cessation programs at the Tom Baker Cancer Centre in Calgary, Alberta, Canada, separate support group sessions were offered for support persons of(More)
Techniques were described for recording trigeminal evoked potentials in humans in response to maxillary gum stimulation. Variations in the responses as a function of stimulating and recording electrode position and stimulus intensity were presented. A standard methodology was proposed in order to obtain the characteristic response repeatedly. The(More)
A retrospective analysis was performed upon 175 patients with Non-Hodgkin's Lymphoma involving the gastrointestinal tract and entered into BNLI trials and studies between 1974-1988. Malignant histiocytosis of the intestine (MHI), which was present in 16 patients, was associated with a survival of less than 25% at 18 months, and probably accounted for the(More)
The proliferative potential of human solid tumours, in vivo, was investigated using bromodeoxyuridine (BrdUrd) incorporation and flow cytometry (FCM). Patients with solid tumours from a variety of sites were injected with 500 mg BrdUrd, intravenously, several hours prior to biopsy or surgical excision. The labelling index (LI), duration of S-phase (Ts) and(More)
Data from a series of 45 patients with Stage I and II non-Hodgkin's lymphoma (NHL) of the thyroid gland were analysed retrospectively to determine the incidence and prognostic significance of histopathological features of tumour origin from mucosa associated lymphoid tissue (MALT). The overall 5- and 10-year cause specific survival from NHL for the series(More)
Auditory evoked potentials were recorded intracranially from the 8th nerve during neurosurgical procedures. The potentials had a large negative peak that occurred 3.0--3.7 msec after the onset of the stimulus (2 000 Hz tone bursts). When these potentials were compared with the scalp recorded brain stem evoked potentials (BSEPs) the intracranial response was(More)
Brain retraction and induced hypotension are surgical adjuncts capable of compromising cerebral blood flow. To evaluate their effects upon brain function, cortical evoked potentials, neurological status and cortical histological changes were determined as a function of graded levels of brain retractor and systemic perfusion pressure in the dog.(More)
WILLIS (1936) defines teratomas as neoplasms composed of multiple tissues foreign to the parts in which they arise, both in benign and malignant forms. Teratomas may occur in any part of the body, the commonest sites being the ovary, testis and mediastinum. The thyroid is numbered among the least common sites, together with the pineal and brain (Willis,(More)