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New gastroprotective ferruginol derivatives with selective cytotoxicity against gastric cancer cells.
The most promising compounds were 11, 13 and 14, presenting a gastroprotective effect higher or similar to that of ferruginol but with a high selectivity towards the tumor AGS cells, and the isobutyrate 4, inactive as a gastroProtective agent, showed selective cytotoxicity against AGS and Hep G2 cells.