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The purpose of this project was to determine whether Contrast Limited Adaptive Histogram Equalization (CLAHE) improves detection of simulated spiculations in dense mammograms. Lines simulating the appearance of spiculations, a common marker of malignancy when visualized with masses, were embedded in dense mammograms digitized at 50 micron pixels, 12 bits(More)
RATIONALE AND OBJECTIVES The purpose of this study was to determine whether contrast-limited adaptive histogram equalization (CLAHE) or histogram-based intensity windowing (HIW) improves the detection of simulated masses in dense mammograms. MATERIALS AND METHODS Simulated masses were embedded in portions of mammograms of patients with dense breasts; the(More)
This study attempts to determine whether intensity windowing (IW) improves detection of simulated calcifications in dense mammograms. Clusters of five simulated calcifications were embedded in dense mammograms digitized at 50-microns pixels, 12 bits deep. Film images with no windowing applied were compared with film images with nine different window widths(More)
Our purpose in this study was to determine the importance of the luminance range of the display system for the detection of simulated masses in mammograms. Simulated masses were embedded in selected portions (512 x 512 pixels) of mammograms digitized at 50 micro pixels, 12 bits deep. The masses were embedded in one of four quadrants in the image. An(More)
The genetics of adaptive shape shift in stickleback: pleiotropy and effect size. Evolution 62:76-85. Environment specific pleiotropy facilitates divergence at the ectodysplasin locus in threespine stickleback. Eye regression in blind Astyanax cavefish may facilitate the evolution of an adaptive behavior and its sensory receptors. BMC biology 11:81. Test: a(More)
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