Marlène Richard

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The localization of 14.3.3 proteins was studied in different subtypes of brain amyloid plaques. We examined paraffin-embedded brain sections of sporadic MV2 Creutzfeldt-Jakob disease (sCJD) with Kuru plaques, sporadic VV2 CJD with plaque-like PrPsc (the abnornal form of prion protein) deposits, variant CJD (vCJD) with florid plaques,(More)
OBJECTIVE Fibrosing alveolitis is a prominent feature of systemic sclerosis (SSc), and accounts for much of the morbidity and mortality of this disease. Sensitive techniques for the detection and monitoring of fibrosing alveolitis could target patients for early therapeutic intervention. The objective of this small pilot study was to assess the frequency(More)
Bilateral castration of male rainbow Trout resulted in increased levels of circulating gonadotropin, as measured by radioimmunoassay, but the response varied depending on the season. In early May the increase was 12 ng/ml after 30 days, when compared to the intact control but later in the month at the time when a peak of gonadotropin level is observed in(More)
Creutzfeldt-Jakob disease (CJD) is characterized by 4 main neuropathological lesions: spongiform change, neuronal loss, astrocytic gliosis, and accumulation of pathological prion protein (PrPsc), which is partially protease-resistant (PrPres). This study focused on spongiform change (SC) in the putamen. Because SC varies from case to case, we investigated(More)
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