Markus Zeilinger

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Despite extensive research effort, ordinary anomaly detection systems still suffer from serious drawbacks such as high false alarm rates due to the enormous variety of network traffic. Also, increasingly fast network speeds pose performance problems to systems which base upon deep packet inspection. In this paper, we address these problems by proposing a(More)
In recent years, much research focused on entropy as a metric describing the “chaos” inherent to network traffic. In particular, network entropy time series turned out to be a scalable technique to detect unexpected behavior in network traffic. In this paper, we propose an algorithm capable of detecting abrupt changes in network entropy time series. Abrupt(More)
Android is an open software platform for mobile devices with a large market share in the smart phone sector. The openness of the system as well as its wide adoption lead to an increasing amount of malware developed for this platform. ANANAS is an expandable and modular framework for analyzing Android applications. It takes care of common needs for dynamic(More)
The aim of the present study was the evaluation and automation of the radiosynthesis of [(11)C]harmine for clinical trials. The following parameters have been investigated: amount of base, precursor concentration, solvent, reaction temperature and time. The optimum reaction conditions were determined to be 2-3mg/mL precursor activated with 1eq. 5M NaOH in(More)
Changes in the expression of the melanin concentrating hormone receptor 1 (MCHR1) are involved in a variety of pathologies, especially obesity and anxiety disorders. To monitor these pathologies in-vivo positron emission tomography (PET) is a suitable method. After the successful radiosynthesis of [(11)C]SNAP-7941-the first PET-Tracer for the MCHR1, we(More)
Patients who are unable to be adequately nourished owing to cerebral dysfunction do not tolerate nasogastric tubes for enteral nutrition well. They are threatened by active or passive dislocation of the tube into the oesophagus with subsequent aspiration. Although these risks are minimized by percutaneous gastrostomy (PEG), aspiration cannot be completely(More)
INTRODUCTION Due to its involvement in a variety of pathologies (obesity, diabetes, gut inflammation and depression), the melanin concentrating hormone receptor 1 (MCHR1) is a new target for the treatment of these lifestyle diseases. We previously presented the radiosynthesis of [(11)C]SNAP-7941, the first potential PET tracer for the MCHR1. METHODS We(More)
Seit Dekaden wird bereits an Anomalieerkennung in Computernetzen geforscht. Maßgebliche Erfolge blieben bis heute allerdings aus. Zwar werden regelmäßig Verfahren publiziert, die auf dem Papier viel versprechende Ergebnisse bringen, doch kaum eines schafft es, auch in der Praxis Einsatz zu finden. Der Beitrag zeigt die Gründe dafür auf und stellt vor, wie(More)
The melanin-concentrating hormone (MCH) system is a new target for the treatment of human disorders. Since the knowledge of the MCH system's involvement in a variety of pathologies (obesity, diabetes, and deregulation of metabolic feedback mechanism) is based on in vitro or preclinical studies, a suitable positron emission tomography (PET) tracer needs to(More)
BACKGROUND The melanin-concentrating hormone receptor 1 (MCHR1), which is highly expressed in the lateral hypothalamus, plays a key role in energy homeostasis, obesity and other endocrine diseases. Hence, there is a major interest in in vivo imaging of this receptor. A PET tracer would allow non-invasive in vivo visualization and quantification of the(More)