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Theano is a Python library that allows to define, optimize, and evaluate mathematical expressions involving multi-dimensional arrays efficiently. Since its introduction, it has been one of the most used CPU and GPU mathematical compilers - especially in the machine learning community - and has shown steady performance improvements. Theano is being actively(More)
The phase shift between oscillations of blood pressure (BP) and Doppler middle cerebral artery flow velocity (MCAFV) reflects continuous cerebral autoregulatory action. It is not known whether a similar phase shift exists for cortical hemodynamics ('microvascular level') assessed by near infrared spectroscopy (NIRS) and what the effects are of pathological(More)
Nonphagocytic NADPH oxidases have recently been suggested to play a major role in the regulation of physiological and pathophysiological processes, in particular, hypertrophy, remodeling, and angiogenesis in the systemic circulation. Moreover, NADPH oxidases have been suggested to serve as oxygen sensors in the lung. Chronic hypoxia induces vascular(More)
Chronic obstructive pulmonary disease (COPD) is one of the most common causes of death worldwide. We report in an emphysema model of mice chronically exposed to tobacco smoke that pulmonary vascular dysfunction, vascular remodeling, and pulmonary hypertension (PH) precede development of alveolar destruction. We provide evidence for a causative role of(More)
The renormalization of the Minimal Supersymmetric Standard Model (MSSM) is presented. We describe symmetry identities that constitute a framework in which the MSSM is completely characterized and renormalizability can be proven. Furthermore, we discuss applications of this framework for the determination of symmetry-restoring counterterms, the gauge(More)
We propose an approach for multi-pose face tracking by association of face detection responses in two stages using multiple cues. The low-level stage uses a two-threshold strategy to merge detection responses based on location, size and pose, resulting in short but reliable tracklets. The high-level stage uses different cues for computing a joint similarity(More)
Dynamic cerebral autoregulation assessed from blood pressure transients can be considerably impaired in severe internal carotid artery (ICA) obstruction. It is unknown whether impaired autoregulation indicates an increased risk of subsequent ischemic events in this situation. 165 patients with ICA stenosis (> 70 %) or occlusion were prospectively followed(More)
BACKGROUND To investigate whether there is: (1) a specific temporal course of cerebral dysautoregulation in acute ischemic stroke, and (2) a separate detrimental effect of recombinant tissue plasminogen activator (rtPA) on autoregulation dynamics in this situation. METHODS We studied 16 patients with acute middle cerebral artery (MCA) occlusion and rtPA(More)
This study deals with the simulation of the experimental study of Roth et al. ~2000! on the interaction of energetic Zn projectiles in partially ionized laser produced carbon targets, and with similar type experiments. Particular attention is paid to the specific contributions of the K and L shell target electrons to electron recombination in the energetic(More)
BACKGROUND Pulmonary hypertension (PH) is a life-threatening disease characterized by vascular remodeling and increased pulmonary vascular resistance. Chronic alveolar hypoxia in animals is often used to decipher pathways being regulated in PH. Here, we aimed to investigate whether chronic hypoxia-induced PH in mice can be reversed by reoxygenation and(More)