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The phase shift between oscillations of blood pressure (BP) and Doppler middle cerebral artery flow velocity (MCAFV) reflects continuous cerebral autoregulatory action. It is not known whether a similar phase shift exists for cortical hemodynamics ('microvascular level') assessed by near infrared spectroscopy (NIRS) and what the effects are of pathological(More)
  • Michael Seimetz, Nirmal Parajuli, Alexandra Pichl, Florian Veit, Grazyna Kwapiszewska, Friederike C. Weisel +19 others
  • 2011
Chronic obstructive pulmonary disease (COPD) is one of the most common causes of death worldwide. We report in an emphysema model of mice chronically exposed to tobacco smoke that pulmonary vascular dysfunction, vascular remodeling, and pulmonary hypertension (PH) precede development of alveolar destruction. We provide evidence for a causative role of(More)
We propose an approach for multi-pose face tracking by association of face detection responses in two stages using multiple cues. The low-level stage uses a two-threshold strategy to merge detection responses based on location, size and pose, resulting in short but reliable tracklets. The high-level stage uses different cues for computing a joint similarity(More)
BACKGROUND To investigate whether there is: (1) a specific temporal course of cerebral dysautoregulation in acute ischemic stroke, and (2) a separate detrimental effect of recombinant tissue plasminogen activator (rtPA) on autoregulation dynamics in this situation. METHODS We studied 16 patients with acute middle cerebral artery (MCA) occlusion and rtPA(More)
— We present a novel approach for vehicle-pedestrian collision risk analysis that incorporates mutual situational awareness, a degree of potential motion coupling and the spatial layout of the environment. The approach uses a Dynamic Bayesian Network (DBN) for modeling the individual object paths; collision risk is subsequently computed by an intersection(More)
A laser-driven, multi-MeV-range ion beamline has been installed at the GSI Helmholtz center for heavy ion research. The high-power laser PHELIX drives the very short (picosecond) ion acceleration on μm scale, with energies ranging up to 28.4 MeV for protons in a continuous spectrum. The necessary beam shaping behind the source is accomplished by applying(More)
  • Matthias Reinhard, Thomas A Gerds, Daniel Grabiak, Philipp R Zimmermann, Markus Roth, Brigitte Guschlbauer +15 others
  • 2007
Cerebral dysautoregulation and the risk of ischemic events in occlusive carotid artery disease ■ Abstract Dynamic cerebral au-toregulation assessed from blood pressure transients can be considerably impaired in severe internal carotid artery (ICA) obstruction. It is unknown whether impaired au-toregulation indicates an increased risk of subsequent ischemic(More)
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