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- Markus M. Knodel, Romina Geiger, +5 authors Gillian Queisser
- Front. Comput. Neurosci.
- 2014

The morphology of presynaptic specializations can vary greatly ranging from classical single-release-site boutons in the central nervous system to boutons of various sizes harboring multiple vesicle release sites. Multi-release-site boutons can be found in several neural contexts, for example at the neuromuscular junction (NMJ) of body wall muscles of… (More)

- Stephan Grein, Martin Stepniewski, Sebastian Reiter, Markus M. Knodel, Gillian Queisser
- Front. Neuroinform.
- 2014

Investigation of cellular and network dynamics in the brain by means of modeling and simulation has evolved into a highly interdisciplinary field, that uses sophisticated modeling and simulation approaches to understand distinct areas of brain function. Depending on the underlying complexity, these models vary in their level of detail, in order to cope with… (More)

- Markus M. Knodel, Arne Nägel, +5 authors Gabriel Wittum
- Computat. and Visualiz. in Science
- 2015

- Markus M Knodel, Dan Bucher, +5 authors Gillian Queisser
- BMC Neuroscience
- 2013

To truly appreciate the myriad of events which relate synaptic function and vesicle dynamics, simulations should be done in a spatially realistic environment. This holds true in particular in order to explain as well the rather astonishing motor patterns which we observed within in vivo recordings which underlie peristaltic contractionsas well as the shape… (More)

Mathematical models of virus dynamics have not previously acknowledged spatial resolution at the intracellular level despite substantial arguments that favor the consideration of intracellular spatial dependence. The replication of the hepatitis C virus (HCV) viral RNA (vRNA) occurs within special replication complexes formed from membranes derived from… (More)

- Markus Knodel, Gillian Queisser, +5 authors Gabriel Wittum
- BMC Neuroscience
- 2011

To truly appreciate the myriad of events which relate synaptic function and vesicle dynamics, simulations should be done in a spatially realistic environment. This holds true in particular in order to explain the rather astonishing motor patterns presented here which we observed within in vivo recordings which underlie peristaltic contractions at a well… (More)

- Markus M Knodel, Daniel B Bucher, Gillian Queisser, Christoph Schuster, Gabriel Wittum
- BMC Neuroscience
- 2009

An important challenge in neuroscience is understanding how networks of neurons go about processing information. Synapses are thought to play an essential role in cellular information processing however quantitative and mathematical models of the underlying physiologic processes that occur at synaptic active zones are lacking. We are generating mathematical… (More)

Using the parallel/orthogonal space method, we calculate the planar two-loop three-point diagram and two rotated reduced planar two-loop three-point diagrams. Together with the crossed topology, these diagrams are the most complicated ones in the two-loop corrections necessary, for instance, for the decay of the Z0 boson. Instead of calculating particular… (More)

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