Markus Hupp

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Aberrant migration of smooth muscle cells (SMCs) is a key feature of restenosis. Since extracellular matrix proteins and their receptors of the integrin family play a critical role in this process, it is instrumental to understand their contribution to cell migration and invasive motility of SMC on the molecular level. Therefore, we investigated the role of(More)
The current SIOP (International Society for Paediatric Oncology)-LGG (low grade glioma) study protocol allows chiasmatic tumours identified as LGG on the basis of neuroradiological characteristics to be treated without histological verification. As some tumours do not respond well to treatment, the search for molecular tissue markers will gain importance(More)
Multiple sclerosis (MS) patients may experience severe local inflammatory skin reactions during disease-modifying therapy with subcutaneously injected interferon-β (IFN-β). It is common clinical practice to switch those patients to an intramuscularly administered formulation, where severe local skin reactions have not been described. Here we report a(More)
Context. Supersonic turbulence is ubiquitous in the interstellar medium and plays an important role in contemporary star formation. Aims. To perform a high-resolution numerical simulation of supersonic isothermal turbulence driven by compressive large-scale forcing and to analyse various statistical properties. Methods. The compressible Euler equations with(More)
The prevalence of symptomatic syringomyelia in patients with chronic spinal cord injury (SCI) is around 4.5%. It is an important cause of treatable neurologic deterioration, although surgical shunting of the syrinx or arachnoid adhesiolysis of tethered elements have unpredictable results. Classically, syrinx extension causes progressive neuropathic pain,(More)
Erklärung Hiermit erkläre ich, dass ich die Dissertation " Integrin α v and Focal adhesion kinase – promising targets to limit smooth muscle cell migration " selbständig angefertigt und keine anderen als die von mir angegebenen Quellen und Hilfsmittel benutzt habe. Ich erkläre außerdem, dass diese Dissertation weder in gleicher oder anderer Form bereits in(More)
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