Markus Gonser

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A fetus, although semi-allogeneic, is usually accepted by the maternal immune system. However, complications, including alloresponsive mechanisms, are thought to be potentially detrimental for a successful pregnancy. Therefore, we compared allogeneic T cell responses of nonpregnant women with the response of healthy pregnant women and pregnant women who(More)
AIMS The aim of this study was to investigate the current prenatal "off-label use" of cytomegalovirus hyperimmunoglobulin (CMV-HIG) in the prevention and treatment of congenital CMV (cCMV) infection, including the long-term outcome of the children. METHODS This retrospective observational study comprised mothers and their children, born between January 1,(More)
OBJECTIVE Abnormally invasive placenta (AIP) poses diagnostic and therapeutic challenges. We analyzed clinical cases with confirmed placenta increta or percreta. DESIGN Retrospective case series. SETTING Multicenter study. POPULATION Pregnant women with AIP. METHODS Chart review. MAIN OUTCOME MEASURES Prenatal detection rates, treatment choices,(More)
  • M. Gonser
  • Archives of Gynecology and Obstetrics
  • 1995
Traditional protocols for oxytocin infusion regimens recommend increases of infusion rate at 15–20 min intervals. However recent clinical studies agree that prolonged intervals of 30-40 or even 60 minutes are superior to shorter dosage intervals in terms of safety and efficacy. These results are in good agreement with recent pharmacologic data on oxytocin(More)
OBJECTIVE Fetal sex determination by ultrasound, and its medical and ethical implications, has been predominantly discussed in mid and late gestation. The development of high resolution ultrasound equipment has provided the possibility of detailed visualization of the fetus in early pregnancy. The present prospective study investigates the feasibility and(More)
Homozygous alpha-thalassaemia Hb Bart is a very rare illness in North America and Western Europe, but is a common cause of NIHF especially in South East Asia. It causes severe hydrops fetalis with lethal outcome and maternal complications as preterm labour, pre-eclampsia and retained placenta. A case report of an immigrant from Laos with preterm labour and(More)
AIM In pregnancies with unilateral placental location, the uteroplacental Doppler flow measurements show significant side-to-side differences. Highly divergent findings seem to be associated with an unfavourable outcome, particularly with preeclampsia. Therefore, we studied the relationship between placental location and subsequent development of(More)