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  • Nan Nan Gao, John Lelay, Marko Z. Vatamaniuk, Sebastian Rieck, Joshua R Friedman, Klaus H. Kaestner
  • Biology, Medicine
  • Genes & development
  • 2008 (First Published: 15 December 2008)
  • The onset of pancreas development in the foregut endoderm is marked by activation of the homeobox gene Pdx1 (IPF1). Pdx1 is essential for the expansion of the pancreatic primordium and theContinue Reading
  • Xiang Di Wang, Marko Z. Vatamaniuk, Shao Kang Wang, Carol A. Roneker, Rebecca A. Simmons, Xingen G. Lei
  • Biology, Medicine
  • Diabetologia
  • 2008 (First Published: 1 August 2008)
  • Aims/hypothesisWe previously observed hyperglycaemia, hyperinsulinaemia, insulin resistance and obesity in Gpx1-overexpressing mice (OE). Here we determined whether these phenotypes were eliminatedContinue Reading
  • Marko Z. Vatamaniuk, Rana K Gupta, Kristen A Lantz, Nicolai M. Doliba, Franz M. Matschinsky, Klaus H. Kaestner
  • Biology, Medicine
  • Diabetes
  • 2006 (First Published: 1 October 2006)
  • Foxa1 (formerly hepatic nuclear factor 3alpha) belongs to the family of Foxa genes that are expressed in early development and takes part in the differentiation of endoderm-derived organs and theContinue Reading