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Consider N entities to be classified (e.g., geographical areas), a matrix of dissimilarity between pairs of entities, a graph H with vertices associated with these entities such that the edges join the vertices corresponding to contiguous entities. The split of a cluster is the smallest dissimilarity between an entity of this cluster and an entity outside(More)
Previous cross-sectional functional magnetic resonance imaging studies have shown that performance monitoring functions continue to develop well into adolescence, associated with increased activation in brain regions important for cognitive control (prefrontal cortex, anterior cingulate cortex, and parietal cortex). To date, however, the development of(More)
Resting state fMRI (RSfMRI) and arterial spin labeling (ASL) provide the field of pharmacological Neuroimaging tool for investigating states of brain activity in terms of functional connectivity or cerebral blood flow (CBF). Functional connectivity reflects the degree of synchrony or correlation of spontaneous fluctuations--mostly in the blood oxygen level(More)
Victimization is a relatively common, yet serious problem, with potentially severe consequences for children's psychosocial and academic functioning. Children who are Deaf or Hard of Hearing (DHH) may be at a higher risk for victimization than hearing children. The aims of the present study were to compare DHH and hearing children on i) self-reported(More)
Ketamine, an NMDA receptor antagonist, is increasingly used to study the link between glutamatergic signaling dysregulation and mood and chronic pain disorders. Glutamatergic neurotransmission and stress corticosteroids (cortisol in human) are critical for Ca(2+) mediated neuroplasticity and behavioral adaptation. The mechanisms of action of glutamatergic(More)
The aim of the current study was to examine the development of equity preferences across adolescence, for boys and girls separately. Participants from 8 to 18 years old (M = 14.09 years; N = 1,216) played four economic allocation games. Analyses revealed a decrease in equity preferences with age and this decrease was stronger for boys than for girls. There(More)
Stress responses to social evaluation are thought to increase during adolescence, which may be due to pubertal maturation. However, empirical evidence is scarce. This study is the first to investigate the relation between pubertal development and biological responses to a social-evaluative stressor longitudinally. Participants performed the Leiden Public(More)
It has been argued that principal component analysis (PCA) is not appropriate for analyzing data conforming to single-peaked response models, also referred to as unfolding models. An overview of these findings is given, which relates them to the distinction between two types of unfolding models; namely, models that are either a quadratic function of the(More)
Magnetic resonance imaging (MRI) is sensitive to structural and functional changes in the brain caused by Alzheimer's disease (AD), and can therefore be used to help in diagnosing the disease. Improving classification of AD patients based on MRI scans might help to identify AD earlier in the disease's progress, which may be key in developing treatments for(More)