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  • F E Rey, Morales Cifuentes, Arash Kiarash, Mark T Quinn, Patrick J. Pagano
  • Chemistry, Medicine
  • Circulation research
  • 2001 (First Publication: 31 August 2001)
  • We previously reported enhanced expression of the p67(phox) and gp91(phox) components of NAD(P)H oxidase in angiotensin (Ang) II-induced hypertension, suggesting de novo assembly in response to AngContinue Reading
  • Masuko Ushio–Fukai, Yan Tang, +7 authors Robert W. Alexander
  • Medicine, Biology
  • Circulation research
  • 2002 (First Publication: 13 December 2002)
  • Vascular endothelial growth factor (VEGF) induces angiogenesis by stimulating endothelial cell proliferation and migration, primarily through the receptor tyrosine kinase VEGF receptor2 (Flk1/KDR).Continue Reading
  • Rhian M Touyz, Xin Chen, +5 authors Ernesto L Schiffrin
  • Medicine, Biology
  • Circulation research
  • 2002 (First Publication: 14 June 2002)
  • A major source of vascular smooth muscle cell (VSMC) superoxide is NAD(P)H oxidase. However, the molecular characteristics and regulation of this enzyme are unclear. We investigated whether VSMCsContinue Reading
  • Lula L. Hilenski, Roza E. Clempus, Mark T Quinn, James D. Lambeth, Kathy K. Griendling
  • Medicine, Biology
  • Arteriosclerosis, thrombosis, and vascular…
  • 2004 (First Publication: 5 February 2004)
  • OBJECTIVE Reactive oxygen species (ROS) that act as signaling molecules in vascular smooth muscle cells (VSMC) and contribute to growth, hypertrophy, and migration in atherogenesis are produced byContinue Reading
  • Patrick J Pagano, John Kellock Clark, M E Cifuentes-Pagano, Shawn M. Clark, Gayle M. Callis, Mark T Quinn
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1997 (First Publication: 23 December 1997)
  • Superoxide anion (O2-) plays a key role in the endogenous suppression of endothelium-derived nitric oxide (NO) bioactivity and has been implicated in the development of hypertension. In previousContinue Reading