Mark Stroh

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Neurotrophins such as nerve growth factor (NGF) may be useful for treating diseases in the central nervous system; our ability to harness the potential therapeutic benefit of NGF is directly related to our understanding of the fate of exogenously supplied factors in brain tissue. We utilized multiphoton microscopy to quantify the dynamic behavior of NGF in(More)
Novae are thermonuclear explosions on a white dwarf surface fueled by mass accreted from a companion star. Current physical models posit that shocked expanding gas from the nova shell can produce x-ray emission, but emission at higher energies has not been widely expected. Here, we report the Fermi Large Area Telescope detection of variable gamma-ray(More)
The Swift X-ray Telescope (XRT) has discovered that flares are quite common in early X-ray afterglows of gamma-ray bursts (GRBs), being observed in roughly 50% of afterglows with prompt follow-up observations. The flares range in fluence from a few per cent to approximately 100% of the fluence of the prompt emission (the GRB). Repetitive flares are seen,(More)
The maximally tolerated dose (MTD) of cytotoxic agents has historical precedence in treating cancer, as it was believed that dose and therapeutic effect are intrinsically linked and that the MTD would provide greatest therapeutic value. With molecularly targeted agents, the premise of preventing toxicity to normal tissues while modulating tumor growth(More)
We present results from a long-term monitoring campaign on the TeV binary LSI +61 • 303 with VERITAS at energies above 500 GeV, and in the 2-10 keV hard X-ray bands with RXTE and Swift, sampling nine 26.5 day orbital cycles between be variable, with all integrated observations resulting in a detection at the 8.8σ The source was detected during active(More)
We report on the results of a long term X-ray monitoring campaign of the galactic binary LS I +61 303 performed by the Rossi X-ray Timing Explorer. This dataset consists of 1 ks pointings taken every other day between 2007 August 28 until 2008 February 2. The observations covered six full cycles of the 26.496 day binary period and constitute the largest(More)
We report on the results of a long term X-ray monitoring campaign of the galactic binary LS I +61 303 performed by the Rossi X-ray Timing Explorer. This dataset consists of 1 ks pointings taken every other day between 2007 August 28 until 2008 February 2. The observations covered six full cycles of the 26.496 day binary period and constitute the largest(More)
Swift-XRT observations of the X-ray emission from gamma ray bursts (GRBs) and during the GRB afterglow have led to many new results during the past two years. One of these exciting results is that ∼1/3 − 1/2 of GRBs contain detectable X-ray flares. The mean fluence of the X-ray flares is ∼10× less than that of the initial prompt emission, but in some cases(More)
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