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  • Sanjiv Sam Gambhir, Eileen M. Bauer, +7 authors Harvey R. Herschman
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2000 (First Published: 14 March 2000)
  • We are developing assays for noninvasive, quantitative imaging of reporter genes with positron emission tomography (PET), for application both in animal models and in human gene therapy. We reportContinue Reading
  • Margaret E. A. Black, Mark Stamatios Kokoris, Peter J. Sabo
  • Biology, Medicine
  • Cancer research
  • 2001 (First Published: 1 April 2001)
  • Cancer suicide gene therapy affords the prospect of using the most optimal genes available because the source of the therapeutic gene is often irrelevant. Currently, there are numerous preclinicalContinue Reading
  • Mark Stamatios Kokoris, Margaret E. A. Black
  • Chemistry, Medicine
  • Protein science : a publication of the Protein…
  • 2002 (First Published: 13 April 2009)
  • Herpes Simplex Virus type 1 (HSV-1) thymidine kinase (TK) is currently the most widely used suicide agent for gene therapy of cancer. Tumor cells that express HSV-1 thymidine kinase are renderedContinue Reading