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Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation
Antigen receptor–mediated production of inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) in lymphocytes triggers the release of Ca2+ from intracellular stores; this release of Ca2+ results in the openingExpand
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Corrigendum: Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation
Jane Tian, Ana Maria Avalos, Su-Yau Mao, Bo Chen, Kannaki Senthil, Herren Wu, Peggy Parroche, Stacey Drabic, Douglas Golenbock, Cherilyn Sirois, Jing Hua, Ling Ling An, Laurent Audoly, Greg La Rosa,Expand
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Phosphoinositide and Inositol Phosphate Analysis in Lymphocyte Activation
Lymphocyte antigen receptor engagement profoundly changes the cellular content of phosphoinositide lipids and soluble inositol phosphates. Among these, the phosphoinositides phosphatidylinositolExpand
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Discovery of 2-amino-6-carboxamidobenzothiazoles as potent Lck inhibitors.
A novel series of 2-amino-6-carboxamidobenzothiazole was discovered to have potent Lck inhibitory properties. A highly efficient chemistry was developed. Also described are the detailed SAR study andExpand
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Isolation and Characterization of a Distinct Subpopulation from the WM115 Cell Line That Resembles In Vitro Properties of Melanoma Cancer Stem Cells
Despite key advances in cancer therapies, malignant tumors, such as melanoma, continue to be one of the leading causes of mortality. Recent debate on whether cancer can originate from aExpand
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842 EFFECTS OF TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION (TENS) ON MUSCLE BLOOD FLOW IN THE TRAPEZIUS MUSCLE AND OVERLYING SKIN
Background and Aims: Laser Doppler flowmetry (LDF) and venous occlusion plethysmography are techniques frequently used in TENS studies to measure blood flow changes in skin and volume changes in aExpand
Discussion Group T07 Shop Field Testing of Gas Turbines and Compressors
has held several engineering positions over his 38 year career at Dresser-Rand Company. The majority of his work experience has been in the thermodynamic performance field of centrifugal compressors.Expand
Discussion Group T11 Shop Field Testing of Gas Turbines and Compressors
Mr. Gary Colby has held several engineering positions over his 38 year career at Dresser-Rand Company. The majority of his work experience has been in the thermodynamic performance field ofExpand