Mark S. Levenson

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This paper discusses some aspects of selecting and testing random and pseudorandom number generators. The outputs of such generators may be used in many cryptographic applications, such as the generation of key material. Generators suitable for use in cryptographic applications may need to meet stronger requirements than for other applications. In(More)
OBJECTIVE To examine the risk of suicidal behaviour within clinical trials of antidepressants in adults. DESIGN Meta-analysis of 372 double blind randomised placebo controlled trials. SETTING Drug development programmes for any indication in adults. PARTICIPANTS 99 231 adults assigned to antidepressants or placebo. Median age was 42 and 63.1% were(More)
BACKGROUND The comparative safety of dabigatran versus warfarin for treatment of nonvalvular atrial fibrillation in general practice settings has not been established. METHODS AND RESULTS We formed new-user cohorts of propensity score-matched elderly patients enrolled in Medicare who initiated dabigatran or warfarin for treatment of nonvalvular atrial(More)
BACKGROUND Although certain drugs that target the renin- angiotensin-aldosterone system are linked to an increased risk for angioedema, data on their absolute and comparative risks are limited. We assessed the risk for angioedema associated with the use of angiotensin converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), and the direct(More)
The problem of determining a consensus value and its uncertainty from the results of multiple methods or laboratories is discussed. Desirable criteria of a solution are presented. A solution motivated by the ISO Guide to the Expression of Uncertainty in Measurement (ISO GUM) is introduced and applied in a detailed worked example. A Bayesian hierarchical(More)
This paper presents a detailed discussion of the technical aspects of the calibration process with emphasis on the definition of the measurand, the conditions under which the calibration results are valid, and the subsequent use of the calibration results in measurement uncertainty statements. The concepts of measurement uncertainty, error, systematic(More)
The U. S. Consumer Product Safety Commission staff uses raking to impute unknown or missing values in fire incident reports. In typical analyses, up to six variables are imputed. These variables describe the cause of the fire and the way that it propagates through a building. Typically, 25 to 40 percent of the values of these variables are unknown. All the(More)
IMPORTANCE All intravenous (IV) iron products are associated with anaphylaxis, but the comparative safety of each product has not been well established. OBJECTIVE To compare the risk of anaphylaxis among marketed IV iron products. DESIGN, SETTING, AND PARTICIPANTS Retrospective new user cohort study of IV iron recipients (n = 688,183) enrolled in the US(More)
We describe the use of Bayesian inference to include prior information about the value of the measurand in the calculation of measurement uncertainty. Typical examples show this can, in effect, reduce the expanded uncertainty by up to 85 %. The application of the Bayesian approach to proving workpiece conformance to specification (as given by international(More)
The Algorithm Testing and Evaluation Program for Coordinate Measurement Systems (ATEP-CMS) is a Special Test Service offered under the NIST Calibration Program. ATEP-CMS evaluates the performance of geometric fitting software used in coordinate measurement systems. It is a Special Test because it is a new type of NIST service, experimental in nature and(More)