Mark R Wheeler

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It is shown that absorption of the excitation light can lead to substantial systematic errors in fluorescence measurements of equilibrium constants for formation of protein-ligand complexes. The assumptions about the optical arrangement of the fluorescence spectrometer involved in the calculation of the correction of this absorption are discussed. A general(More)
Barrett esophagus (BE) is a preneoplastic condition that predisposes to esophageal adenocarcinoma and is a consequence of prolonged gastroesophageal reflux disease. The condition is mainly seen in adults and is thought to be a complex disease in which individual genetic predisposition interacts with environmental stimuli. The aim of our study was to(More)
References: Archer, M.A., J.P. Phelan, K.A. Beckman, and M.R. Rose 2003, Evolution 60: 1435–1444; Ballard, J.W.O., R.G. Melvin, and S.J. Simpson 2008, Journal of Insect Physiology 54: 1371-1376; Bock, I.R., and M.R. Wheeler 1972, University of Texas Publ. 7213: 1-102; Boucher, L., and J. Huignard 1987, Journal of Insect Physiology 33: 949-957; Brandy, R.,(More)