Mark R Payne

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In response to ionizing radiation (IR), cells delay cell cycle progression and activate DNA repair. Both processes are vital for genome integrity, but the mechanisms involved in their coordination are not fully understood. In a mass spectrometry screen, we identified the adenosine triphosphate-dependent chromatin-remodeling protein CHD4 (chromodomain(More)
We present a unique view of mackerel (Scomber scombrus) in the North Sea based on a new time series of larvae caught by the Continuous Plankton Recorder (CPR) survey from 1948-2005, covering the period both before and after the collapse of the North Sea stock. Hydrographic backtrack modelling suggested that the effect of advection is very limited between(More)
Rising ocean temperatures are causing marine fish species to shift spatial distributions and ranges, and are altering predator-prey dynamics in food webs. Most documented cases of species shifts so far involve relatively small species at lower trophic levels, and consider individual species in ecological isolation from others. Here, we show that a large(More)
OBJECTIVE To investigate the reliability of a radiographic measurement procedure that uses a computer and sonic digitizer to determine projected spinal displacements from an ideal normal position. DESIGN A blind, repeated-measure design was used. Anteroposterior lumbopelvic radiographs were presented to each of 3 examiners in random order. Each film was(More)
It has been suggested that observed spatial variation in mackerel fisheries, extending over several hundreds of kilometers, is reflective of climate-driven changes in mackerel migration patterns. Previous studies have been unable to clearly demonstrate this link. In this paper we demonstrate correlation between temperature and mackerel(More)
OBJECTIVE To investigate the reliability of a new radiographic measurement of axial rotation and lateral bending on anterior-posterior cervical views by using a computer and sonic digitizer. DESIGN A blind, repeated-measure design was used. Anteroposterior cervicothoracic radiographs were presented to each of 3 examiners in random order. Each film was(More)
Functional traits, rather than taxonomic identity, determine the fitness of individuals in their environment: traits of marine organisms are therefore expected to vary across the global ocean as a function of the environment. Here, we quantify such spatial and seasonal variations based on extensive empirical data and present the first global biogeography of(More)