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A chloramphenicol-resistance gene (cml) was introduced into the Lactobacillus plantarum gene encoding conjugated bile acid hydrolasc (cbh) on a ColEl replicon. This plasmid which is nonreplicative in(More)
The synthesis of plasmid DNA and of RNA encoded by the replication protein gene (rep) of plasmid p 353-2 of Lactobacillus pentosus was studied for the wildtype plasmid and for a mutant plasmid with a(More)
Safe live vector systems are being developed for oral delivery of antigens. A transformation system for indigenous Lactobacillus species of the gastrointestinal tract is described. Model systems were(More)