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Divergence in gene regulation can play a major role in evolution. Here, we used a phylogenetic framework to measure mRNA profiles in 15 yeast species from the phylum Ascomycota and reconstruct the evolution of their modular regulatory programs along a time course of growth on glucose over 300 million years [corrected]. We found that modules have diverged(More)
Evolutionary principles of modular gene regulation in yeasts. " eLife 2, no. 0 (January 8, 2013): e00603-e00603. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Abstract Divergence in gene regulation can play a major role in evolution. Here, we used a phylogenetic framework to measure(More)
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