Mark McFarland

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The Texas Digital Library is a cooperative initiative of Texas universities. One of TDL's core services is a federated collection of ETDs from its member schools. As this collection grew, the need for tools to manage the content exchange from the local to the federated repository became evident. This paper presents our experiences adding harvesting support(More)
Ghrelin is a 28-amino acid peptide hormone produced in the stomach. It binds to the growth hormone secretagogue receptor 1a (GHS-R1a), a class A G-protein-coupled receptor. In the present study, we describe the design, synthesis and characterization of a truncated, 18-amino acid analog of ghrelin conjugated to a fluorescent molecule, fluorocein(More)
M any people try to put the growth, development and eventual yield of the grain sorghum plant into a simple formula, when it is a complex series of many processess and interactions. Only after decades of research, the effects and interactions of fertility, row and plant spacing, planting date, environmental conditions (water, temperature, etc.), insects,(More)
The Texas Digital Library is a consortium of universities organized to provide a single digital infrastructure for the scholarly activities of Texas universities. The four current Association of Research Libraries (ARL) universities and their systems comprise more than 40 campuses, 375,000 students, 30,000 faculty, and 100,000 staff; while non-ARL(More)
We describe the implementation of a statewide system for managing and preserving electronic theses and dissertations (ETDs) from Texas universities. We further explain the theoretical, technical and political issues that arose during the implementation of this system. These issues range from technical components developed by TDL 'such as a customized(More)
BACKGROUND Ghrelin is a natural growth hormone secretagogue (GHS) that is co-expressed with its receptor GHSR in human prostate cancer (PCa) cells. Imaging probes that target receptors for ghrelin may delineate PCas from benign disease. The specificity of a novel ghrelin-imaging probe for PCa over normal tissue or benign disease was assessed. METHODS A(More)
The ghrelin receptor, also known as the growth hormone secretagogue receptor 1a (GHS-R1a), is a G-protein coupled receptor that is differentially expressed in healthy tissue and several cancers, including prostate, testicular, and ovarian. Selectively targeting the ghrelin receptor using fluorine-18 tagged entities would allow localization and visualization(More)