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BACKGROUND Pharmaceutical clinical trials are primarily conducted across many countries, yet recruitment numbers are frequently not met in time. Electronic health records store large amounts of potentially useful data that could aid in this process. The EHR4CR project aims at re-using EHR data for clinical research purposes. OBJECTIVE To evaluate whether(More)
INTRODUCTION This article is part of the Focus Theme of METHODS of Information in Medicine on "Managing Interoperability and Complexity in Health Systems". BACKGROUND Primary care data is the single richest source of routine health care data. However its use, both in research and clinical work, often requires data from multiple clinical sites, clinical(More)
OBJECTIVE Biomedical research increasingly relies on the integration of information from multiple heterogeneous data sources. Despite the fact that structural and terminological aspects of interoperability are interdependent and rely on a common set of requirements, current efforts typically address them in isolation. We propose a unified ontology-based(More)
OBJECTIVES To perform a requirements analysis of the barriers to conducting research linking of primary care, genetic and cancer data. METHODS We extended our initial data-centric approach to include socio-cultural and business requirements. We created reference models of core data requirements common to most studies using unified modelling language(More)
Copyright and reuse: The Warwick Research Archive Portal (WRAP) makes this work by researchers of the University of Warwick available open access under the following conditions. Copyright © and all moral rights to the version of the paper presented here belong to the individual author(s) and/or other copyright owners. To the extent reasonable and(More)
  • A Geissbuhler Personalized, Health Informatics, +34 authors D Kubias
  • 2017
* The complete papers can be accessed in the Yearbook's full electronic version, provided that the article is freely accesible or that your institution has access to the respective journal. Effectiveness of mobile phone short message service on diabetes mellitus management; the SMS-DM study. Factors affecting home care patients' acceptance of a web-based(More)
The HL7 RIM (Reference Information Model) is a commonly used standard for the exchange of clinical data and can be employed for integrating the patient care and clinical research domains. Yet it is not sufficiently well specified to ensure a canonical representation of structured clinical data when used for the automated evaluation of eligibility criteria(More)
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