Mark Lindemann

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Tremor is defined as rhythmic oscillatory activity of body parts. Four physiological basic mechanisms for such oscillatory activity have been described: mechanical oscillations; oscillations based on reflexes; oscillations due to central neuronal pacemakers; and oscillations because of disturbed feedforward or feedback loops. New methodological approaches(More)
OBJECTIVES It has been well established that peripheral mechanical resonant factors as well as central mechanisms may play a role in the generation of physiological tremor (PT). Furthermore it has been postulated that subject's attributes like age and sex might influence PT. The present study was designed to quantify these influences on PT in a large normal(More)
The tremors of Parkinson's disease (PD) and essential tremor (ET) are traditionally considered to depend on a central oscillator producing rhythmic activation of the motoneurones of all extremities. To test this hypothesis, we have compared electromyographic tremor activity in different muscles of the affected limbs using cross spectral analysis, including(More)
OBJECTIVES Postural tremor is a regularly encountered side effect of amitriptyline which can be strong enough to cause discontinuation of therapy. The aim was to characterise amitriptyline induced tremor and to assess if the central or reflex component of physiological tremor was modulated by this drug. METHODS The postural hand tremor was measured in 15(More)
A “secure system” should be secure—but should also be a system that achieves some particular functionality. A family of secure systems that our group has been investigating (and building) are high-end secure coprocessors: devices that combine a general-purpose computing environment with high-performance cryptography inside a tamper-responding secure(More)
In neurophysiology, time delays between concurrently measured time series are usually estimated from the slope of a straight line fitted to the phase spectrum. We point out that this estimate is valid only in the case in which, one signal is a mere time-delayed copy of the other one. We present a procedure for delay estimation that applies to a much wider(More)
Over the last several years, our research team built a commercially-offered secure coprocessor that, besides other features, offers high-speed DES: over 20 megabytes/second. However, it obtains these speeds only on operations with large data lengths. For DES operations on short data (e.g., 8-80 bytes), our commercial offering was benchmarked at less than 2(More)
W ork leading toward the IBM 4758 started, arguably, in the 1980s when the Abyss project began exploring techniques to build tamper-responsive hardware and use that technology to protect against software piracy. Influenced by this earlier work, we sought to build a secure coprocessor, defined as a tamper-responding device derived from the Abyss, Citadel,(More)
W ork leading toward the IBM 4758 started, arguably, in the 1980s when the Abyss project began exploring techniques to build tamper-responsive hardware and use that technology to protect against software piracy. Influenced by this earlier work, we sought to build a secure coprocessor, defined as a tamper-responding device derived from the Abyss, Citadel,(More)