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Understanding the neural circuitry of the retina requires us to map the connectivity of individual neurons in large neuronal tissue sections and analyze signal communication across processes from the electron microscopy images. One of the major bottlenecks in the critical path is the image mosaicing process where 2D slices are assembled from scanned(More)
In this paper, we characterize the range of features that can be extracted from an Morse-Smale complex and describe a unified query language to extract them. We provide a visual dictionary to guide users when defining features in terms of these queries. We demonstrate our topology-rich visualization pipeline in a tool that interactively queries the MS(More)
To study the relationship between ATP and each of three R-values (R248, R250 and R258) in beef longissimus dorsi muscle data, appropriate mathematical functional forms were estimated by the Box-Cox transformation and then tested for linearity. Two separate tests for linearity indicated that the relationships between ATP and the three R-values were(More)
We live in a world of ever-increasing amounts of information that is not only dynamically changing but also dramatically changing in complexity. This trend of “information overload” has quickly overwhelmed our capabilities to explore, hypothesize, and thus fully interpret the underlying details in these data. To further complicate matters, the computer(More)
Extracting isosurfaces represented as high quality meshes from three-dimensional scalar fields is needed for many important applications, particularly visualization and numerical simulations. One recent advance for extracting high quality meshes for isosurface computation is based on a dynamic particle system. Unfortunately, this state-of-the-art particle(More)
As we continue toward exascale, scientific data volume is continuing to scale and becoming more burdensome to manage. In this paper, we lay out opportunities to enhance state of the art data management techniques. We emphasize well-principled data compression, and using it to achieve progressive refinement. This can both accelerate I/O and afford the user(More)
In tetrahedral mesh generation, the constraints imposed by adaptive element size, good tetrahedral quality (shape measured by some local metric), and material boundaries are often in conflict. Attempts to satisfy these conditions simultaneously frustrate many conventional approaches. We propose a new strategy for boundary conforming meshing that decouples(More)
BACKGROUND The proposed 2015 US Preventive Services Task Force guidelines recommend diabetes screening for individuals ≥45 years or demonstrating other risk factors for dysglycemia. Still, many patients with dysglycemia remain undiagnosed, and opportunities for early intervention are lost. METHODS To test novel approaches for diagnosis using the(More)