Learn More
BACKGROUND Urban slum populations in Africa continue to grow faster than national populations. Health strategies that focus on non-communicable diseases (NCD) in this segment of the population are generally lacking. We determined the prevalence of diabetes and associated cardiovascular disease (CVD) risk factors correlates in Kibera, Nairobi's largest slum.(More)
BACKGROUND Highly active antiretroviral therapy (HAART) has dramatically reduced AIDS morbidity and mortality, however long-term metabolic consequences including dysglycaemia and dyslipidemia have raised concern regarding accelerated cardiovascular disease risk. OBJECTIVE To determine the period prevalence of dyslipidemia and dysglycaemia in HIV-infected(More)
OBJECTIVE To evaluate the utility of Total Lymphocyte Count (TLC) as a surrogate marker for CD4 + T cell count in antiretroviral (ARV) treatment initiation in a Kenyan population of HIV seropositive patients at Kenyatta National Hospital. DESIGN Cross-sectional descriptive study. SETTING Kenyatta National Hospital, HIV treatment and follow-up outpatient(More)
We explore in this paper to waht extent future implied volatility surfaces can be assigned by a trader without incurring the risk of modelindependnt arbitrage. We give precise meaning to the concepts of floating and forward-propagated smile, and show under what condtions such smiles can be arbitrage free. We introduce a mechanism to produce future(More)
OBJECTIVE To determine the prevalence of acute coronary syndromes among type 2 diabetic patients presenting to Accident and Emergency department. DESIGN Prospective cross-sectional study. SETTING Kenyatta National Hospital, a tertiary teaching and referral hospital. SUBJECTS Type 2 diabetic patients with ischaemic electrocardiograms (ECG). MAIN(More)
OBJECTIVE To determine the prevalence of HCV and HCV/HIV co-infection among medical in-patients at the Kenyatta National Hospital. DESIGN Prospective cross-sectional descriptive study. SETTING Kenyatta National Hospital, a tertiary referral and teaching hospital, in-patient department SUBJECTS HIV/AIDS and HIV negative in-patients at KNH medical(More)
BACKGROUND Urbanisation has been described as a key driver of the evolving non-communicable disease (NCD) epidemic. In Africa, hypertension is the commonest cardiovascular problem. We determined the prevalence and risk factor correlates of hypertension in the largest Nairobi slum. METHODS In 2010 we conducted a population-based household survey in Kibera,(More)
We present an extension of the LIBOR market model which allows for stochastic instantaneous volatilities of the forward rates in a displaced diffusion setting. We show that virtually all the powerful and important approximations that apply in the deterministic setting can be successfully and naturally extended to the stochastic volatility case. In(More)
BACKGROUND Coronary artery disease (CAD) is a growing epidemic on the African continent. It remains uncertain whether the risk factors identified as contributing to CAD in white populations contribute to a similar extent to CAD incidence in black populations. No data of the local population exists that is based on the coronary angiogram (CA). OBJECTIVES(More)