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  • Panayiotis A Procopiou, Rachael Ann Ancliff, +15 authors Michael D. Woodrow
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1 December 2007
  • A series of ketopiperazines were prepared and evaluated for their activity as histamine H 3 antagonists. From investigation of the tertiary basic center in the aminopropyloxyphenyl template, the 2(Continue Reading
  • Panayiotis A Procopiou, Esme Joan Bailey, +7 authors Meenaxi Sareen
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1 September 1994
  • Squalestatin analogues modified in the C1 side chain were prepared and evaluated for their ability to inhibit rat liver microsomal and Candida squalene synthase (SQS) in vitro. While maintaining theContinue Reading
  • Jeremy C. Prodger, Mark James GlaxoSmithKline Bamford, +4 authors Victoria Sáez
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry
  • 1 June 1996
  • Analogues of sialyl Lewis X have been synthesized that feature replacement of the N-acetylglucosamine residue with C2-symmetric diols. The diols used contain different levels of torsional constraintContinue Reading