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  • John C. Byrd, Krzysztof Mrózek, +16 authors Clara D. Bloomfield
  • Medicine
  • Blood
  • 2002 (First Publication: 1 August 2002)
  • We analyzed prospectively 1213 adults with de novo acute myeloid leukemia (AML) to ascertain the prognostic impact of cytogenetic abnormalities on complete remission (CR) rate, 5-year cumulativeExpand
  • Jan O. Korbel, Tal Tirosh-Wagner, +30 authors Julie R. Korenberg
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2009 (First Publication: 21 July 2009)
  • Down syndrome (DS), or trisomy 21, is a common disorder associated with several complex clinical phenotypes. Although several hypotheses have been put forward, it is unclear as to whether particularExpand
  • Clara D. Bloomfield, D Lawrence, +9 authors Robert J. Mayer
  • Medicine
  • Cancer research
  • 1998 (First Publication: 15 September 1998)
  • Advances in the treatment of acute myeloid leukemia (AML) have occurred with the introduction of new therapies including high-dose cytarabine and the identification of powerful prognostic factorsExpand
  • Krzysztof Mrózek, Guido Marcucci, +18 authors Clara D. Bloomfield
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2012 (First Publication: 20 December 2012)
  • PURPOSE To evaluate the prognostic significance of the international European LeukemiaNet (ELN) guidelines for reporting genetic alterations in acute myeloid leukemia (AML). PATIENTS AND METHODS WeExpand
  • Guido Marcucci, Krzysztof Mrózek, +13 authors Clara D. Bloomfield
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2005 (First Publication: 20 August 2005)
  • PURPOSE Because both t(8;21) and inv(16) disrupt core binding factor (CBF) in acute myeloid leukemia (AML) and confer relatively favorable prognoses, these cytogenetic groups are often treatedExpand
  • Yi Kong Keung, Michael H. Beaty, Bayard L. Powell, István Molnár, David H. Buss, Mark J. Pettenati
  • Biology, Medicine
  • Leukemia research
  • 2004 (First Publication: 1 June 2004)
  • We conducted a retrospective study to define the significance of Philadelphia chromosome (Ph) in myelodysplastic syndrome and acute leukemia in the adults at this institution and the literature wasExpand
  • Mark J. Pettenati, Panuganti N. Rao, +7 authors Michael Denis Higgins
  • Biology, Medicine
  • American journal of medical genetics
  • 1995 (First Publication: 16 January 1995)
  • We present a large review of 446 cases of paracentric inversions (PAI), including 120 new cases, to assess their incidence, distribution, inheritance, modes of ascertainment, interchromosomalExpand
  • Sherif S. Farag, Kellie J. Archer, +12 authors Clara D. Bloomfield
  • Medicine
  • Blood
  • 2006 (First Publication: 1 July 2006)
  • We investigated the relative prognostic significance of cytogenetics in 635 adult acute myeloid leukemia (AML) patients 60 years of age or older treated on front-line protocols. Classification treesExpand