Mark J. Webb

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Comprehensive global climate models are the only tools that account for the complex set of processes which will determine future climate change at both a global and regional level. Planners are typically faced with a wide range of predicted changes from different models of unknown relative quality, owing to large but unquantified uncertainties in the(More)
Processes in the climate system that can either amplify or dampen the climate response to an external perturbation are referred to as climate feedbacks. Climate sensitivity estimates depend critically on radiative feedbacks associated with water vapor, lapse rate, clouds, snow, and sea ice, and global estimates of these feedbacks differ among general(More)
A methodology is described for probabilistic predictions of future climate. This is based on a set of ensemble simulations of equilibrium and time-dependent changes, carried out by perturbing poorly constrained parameters controlling key physical and biogeochemical processes in the HadCM3 coupled ocean-atmosphere global climate model. These (ongoing)(More)
In addition to influencing climatic conditions directly through radiative forcing, increasing carbon dioxide concentration influences the climate system through its effects on plant physiology. Plant stomata generally open less widely under increased carbon dioxide concentration, which reduces transpiration and thus leaves more water at the land surface.(More)
Vanilloid receptors (VR1) were cloned from human and rat dorsal root ganglion libraries and expressed in Xenopus oocytes or Chinese Hamster Ovary (CHO) cells. Both rat and human VR1 formed ligand gated channels that were activated by capsaicin with similar EC(50) values. Capsaicin had a lower potency on both channels, when measured electrophysiologically in(More)
This report describes the characterisation of cloned rat and human bradykinin B1 receptors in African green monkey kidney fibroblast (Cos-7) cells. A ligand binding assay with [3H]des-Arg10-kallidin was used to compare their pharmacology with respect to known bradykinin B1 and B2 receptor ligands. In addition, the pharmacology of T-kinin and its' derivative(More)
Sandrine Bony, Mark Webb, Christopher Bretherton, Stephen Klein, Pier Siebesma, George Tselioudis and Minghua Zhang 1: Laboratoire de Météorologie Dynamique, IPSL, CNRS, UPMC, Paris, France 2: Hadley Centre for Climate Prediction and Research, Met Office, Exeter, UK 3: Department of Atmospheric Sciences, University of Washington, Seattle, WA, USA 4:(More)
[1] To assess the current status of climate models in simulating clouds, basic cloud climatologies from ten atmospheric general circulation models are compared with satellite measurements from the International Satellite Cloud Climatology Project (ISCCP) and the Clouds and Earth’s Radiant Energy System (CERES) program. An ISCCP simulator is employed in all(More)