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PURPOSE To evaluate patient characteristics, indications, and outcomes of pediatric keratoplasty, and to identify variables that may help predict poor surgical outcomes. METHODS The authors performed a retrospective chart review of penetrating keratoplasty performed in children 14 years and younger between 1991 and 2006. Primary keratoplasty data were(More)
BACKGROUND The recent availability of genetic analyses has demonstrated the shortcomings of the current phenotypic method of corneal dystrophy classification. Abnormalities in different genes can cause a single phenotype, whereas different defects in a single gene can cause different phenotypes. Some disorders termed corneal dystrophies do not appear to(More)
PURPOSE The Cornea Donor Study (CDS) is an ongoing study that is being conducted to determine whether donor age is related to long-term corneal graft survival. Characteristics of the donor population have been evaluated with respect to donor age, endothelial cell density, and death to preservation interval. METHODS Within the context of a prospective,(More)
OBJECTIVE To determine whether graft survival over a 5-year follow-up period using corneal tissue from donors older than 65 is similar to graft survival using corneas from younger donors. DESIGN Multicenter prospective, double-masked, controlled clinical trial. PARTICIPANTS One thousand ninety subjects undergoing corneal transplantation for a(More)
OBJECTIVE To identify baseline (donor, recipient, and operative) factors that affect endothelial cell loss following penetrating keratoplasty for a moderate-risk condition (principally Fuchs dystrophy or pseudophakic or aphakic corneal edema). METHODS In a subset (n = 567) of Cornea Donor Study participants, preoperative and postoperative endothelial cell(More)
Rosacea is a common skin disease that frequently involves the eye. Although the pathogenesis of the disease remains undefined, recent findings suggest that an altered inflammatory response plays an important role in both cutaneous and ocular rosacea. Ocular manifestations include lid and ocular surface alterations. Chronic inflammation can lead to corneal(More)
PURPOSE The aim of this study was to evaluate both the indications for and results of fitting the Jupiter Scleral Lens in patients with corneal abnormalities. METHOD This was a retrospective case review of 63 patients (107 eyes) fitted with scleral lenses between October 2009 and March 2011 at the UC Davis Eye Center. RESULTS Sixty-three percent of 107(More)
PURPOSE To report three cases of infectious crystalline keratopathy caused by non-tuberculous mycobacteria after LASIK surgery. METHODS Interventional case reports and literature review. RESULTS Infectious keratitis with clinical features of crystalline keratopathy after LASIK is described. Culture revealed Mycobacterium chelonae from the corneal(More)
Two male and four female patients had posterior corneal vesicles and scalloped lesions. Ages ranged from 7 to 24 years. Uncorrected visual acuities were 6/6 or better OU. All cases were unilateral. There was no other ocular abnormality. The lesions were at the level of Descemet's membrane and endothelium. Results of specular microscopic examination(More)