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The validity of the conventional esophageal balloon technique as a measure of pleural pressure was tested in 10 subjects in sitting, supine, and lateral positions by occluding the airways at end-expiration and measuring the ratio of changes in esophageal (delta Pes) and mouth pressure (delta Pm) during the ensuing spontaneous occluded inspiratory efforts.(More)
We found that the transport of gases in oscillating gas columns was proportional to oscillation frequency and the square of oscillation amplitude. When these results were applied to high-frequency oscillation and high-frequency jet ventilation in dogs, alveolar ventilation was proportional to frequency and to the square of tidal volume, and inversely(More)
We measured lung compliance, pulmonary flow-resistance, and expiratory reserve volume (ERV) in ten healthy young adults in sitting, supine, and lateral positions. Average lung compliance was 0.21 in sitting, 0.19 in lateral and 0.16 L.cm H2O-1 in supine positions. The change was significant (p less than 0.01) between sitting and supine position.(More)
OBJECTIVES a) To discuss the components of the work of breathing using an established physiologic model (Campbell diagram); b) to describe the requirements of a monitor to measure work; and c) to discuss the implications and relevance for assessing the work of breathing of ventilator-dependent patients. DATA SOURCES Relevant articles from the medical and(More)
Three experiments were conducted to determine if a representation of the movement environment is functional in the organization and control of limb movements, when direct visual contact with the environment is prevented. In Experiment 1, a visual rearrangement procedure was employed to show that a representation of the environment that provides inaccurate(More)
Fifty healthy participants took part in a double-blind placebo-controlled study in which they were either given auditory alpha activity (8-12Hz) training (N=18), random beta training (N=12), or no training at all (N=20). A novel wireless electrode system was used for training without instructions, involving water-based electrodes mounted in an audio(More)
A body plethysmographic technique designed to detect small degrees of uneven ventilation in the lungs is presented. The technique is based on the same theoretical model as the frequency dependence of compliance. It has the advantage of requiring little time, no cooperation by the subject and no computation. Signs of uneven ventilation were found in 3 of the(More)
We measured physical working capacity at a heart rate of 170 bpm (PWC170) and diffusing capacity for carbon monoxide (DLCO) in two groups of children ranging in age from 9 to 17 years. One group was formed of highly trained competitive swimmers and the other of age, sex and size matched untrained counterparts. Bicycle ergometry was used to establish PWC170.(More)
The distensibility of the upper airways was found to range in 8 subjects between 0.01 and 0.001 L/cm H2O. This distensibility may cause a number of errors in standard respiratory measurements in normal subjects and in patients with airway obstruction due to delays in pressure and flow equilibration between alveoli and mouth. The error include overestimation(More)
The purpose of this study was to determine if the interrupter technique, a noninvasive method for measuring airflow resistance, could be used to assess airway obstruction in children. In 107 children (74 with asthma, 12 with cystic fibrosis, and 21 without lung disease) conductance (mostly of airways) measured with the interrupter technique (Gint) was(More)