Mark Hofman

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We would like to thank Professor Axel for the comments related to our study. The dark-rim artifact in cardiac first pass perfusion images has been related in the literature to a number of potential sources; cardiac motion of the heart walls, interface of susceptibility change, and Gibbs ringing. The intensity of the artifact due to motion is determined by(More)
Interleukin-6 (IL-6), ein 21-kDa-Glykoprotein, spielt als proinflammtorisches Zytokin eine wichtige Rolle in der akuten Immunantwort. IL-6 trägt daneben aber auch zur Aufrecherhaltung einer chronischen Entzündung und zur Entstehung verschiedener Autoimmunerkrankungen bei. Bisher ist der IL-6-Rezeptor-Antikörper Tocilizumab (TCZ, RoActemtra®) der einzige(More)
PURPOSE Four-dimensional CT (4D-CT) ventilation imaging has been developed as a complement to nuclear medicine (NM) based methods, but has not yet been validated against a quantitative NM based standard. We are performing the first such study with positron emission tomography using 68 Ga-labelled nanoparticles (Galli-PET). METHODS Respiratory correlated(More)
PURPOSE To date, lung CT-ventilation imaging has been based on quantification of local breathing-induced changes in Hounsfield Units (HU) or volume. This work investigates the use of a stress map resulting from a biomechanical deformable image registration (DIR) algorithm as a metric of the ventilation function. METHOD Eight lung cancer patients(More)
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