Mark Girzadas

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A ceramide glycanase (CGase activity has been characterized from lactating rat mammary tissue which cleaves the glycosidic bond between sphingosine and the glucose chain of a glycosphingolipid (GSL) thus liberating the intact oligosaccharide chain from a GSL. The majority (65%) of the hydrolase activity was detected in the supernatant fraction when the rat(More)
The ceramide glycanase (CGase) activities, which cleave the intact oligosaccharide chain and the ceramide moiety of a glycosphingolipid, have been characterized from two mammalian sources. The enzymatic activities are almost comparable in rabbit and rat mammary tissues. The majority of the activities has been concentrated in the soluble fraction which could(More)
BACKGROUND The detection of coronary anomalies is of major clinical significance. Coronary anomalies have been identified as a frequent cause of sudden death, particularly in young athletes. Multiple series have successfully demonstrated the ability of 64-slice computed tomography (CT) to identify coronary anomalies. However, the relationship of these(More)
An asymptomatic, athletic 53-year-old man was evaluated for an abnormal life insurance electrocardiogram (ECG) that showed deep Twave inversions (15 mm) across the anterior leads (Panel A). He was a passionate cyclist and cycled more than 100 miles per week. The abnormal ECG prompted a transthoracic echocardiogram (TTE) for evaluation of apical hypertrophic(More)
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