Mark Elkins

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QUESTION Does inspiratory muscle training improve inspiratory muscle strength in adults receiving mechanical ventilation? Does it improve the duration or success of weaning? Does it affect length of stay, reintubation, tracheostomy, survival, or the need for post-extubation non-invasive ventilation? Is it tolerable and does it cause adverse events? DESIGN(More)
BACKGROUND Inhalation of the enzyme dornase alfa reduces sputum viscosity and improves clinical outcomes of people with cystic fibrosis. OBJECTIVES To determine the effect of timing of dornase alfa inhalation on measures of clinical efficacy in people with cystic fibrosis (in relation to airway clearance techniques or time of day). SEARCH STRATEGY(More)
BACKGROUND Inhalation of hypertonic saline improves sputum rheology, accelerates mucociliary clearance and improves clinical outcomes of people with cystic fibrosis. OBJECTIVES To determine whether the timing of hypertonic saline inhalation (in relation to airway clearance techniques or in relation to time of day) has an impact on its clinical efficacy in(More)
In order to publish the highest quality randomised trials, Australian Journal of Physiotherapy employs several complementary processes. The first is to actively seek high quality trials. We search clinical trial registers and conference proceedings to identify well conducted trials and invite the investigators to publish with AJP. Next, the AJP Author(More)
Agreement about the meaning of technical terms is valuable for communication within a health profession. It facilitates mutual understanding during communication about patients and their management, research, education, and professional issues. However, inconsistencies are common in the use of technical terms in healthcare (Cimino et al 1994, Schulz et al(More)