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It was previously reported that 3-alkoxybenzo[b]thiophene-2-carboxamides exemplified by 1, 5-methoxy-3-(1-methylethoxy)benzo[b]thiophene-2-carboxamide, decreased the adherence of neutrophils to(More)
In our search for novel dual inhibitors of cyclooxygenase and 5-1ipoxygenase, a series of 3,5-di-tbutyl-styryl heterocycles have been identified. These compounds are active in a variety of models of(More)
OBJECTIVE To evaluate the effects of the phospholipase A2 (PLA2) inhibitor manoalide on cartilage degradation, stromelysin expression, and inflammatory cell accumulation in rabbits treated(More)